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Technical Knowledge

This study developed a field-deployable monitoring system, the BioAerosol Detection Device (BADD), capable of real-time differential measurement of airborne bacterial and fungal concentrations in indoor environments. Utilizing the principle that bacteria lyse faster than fungi due to differences in their cell wall structures, the system features a dual optofluidic module that performs sequential lysis and time-resolved analysis from a single sample. By addressing the limitation of long waiting times inherent in conventional culture-based methods, this system can serve as a valuable complementary tool for indoor bioaerosol exposure surveillance and early risk screening.

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Although low-cost optical dust sensors are widely used in a variety of fields, issues regarding the reliability of measurement data have been continuously raised due to the absence of a standardized calibration method. Existing calibration methods (such as large-scale chamber tests and field co-location tests) are time-consuming and make it difficult to evaluate how well a sensor responds to rapidly changing environments (response characteristics). To overcome these limitations, this study developed a new sensor performance evaluation method utilizing an "exponentially decaying particle concentration

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  A compact fluidized bed test particle generator for the field inspection of PM-2.5 sensors was developed and its performance was evaluated, enhancing portability by operating without a separate compressed air supply system. By adjusting the characteristic parameter, the study succeeded in achieving highly reproducible concentration control that satisfies the requirements of the guidebook (generating around 50ug/m^3 for 1–10 minutes and 25ug/m^3 for 11–20 minutes), thereby confirming its applicability as a field inspection equipment.

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This study presented dosimetry and dose metric considerations for a new approach method (NAM) in inhalation toxicity testing utilizing an air-liquid interface (ALI) system to replace traditional animal experimentation. By generating nano-sized NaCl aerosols and exposing a 6-transwell system (HIVIS) for two hours, it was confirmed that particles deposited highly uniformly across individual transwells. Through real-time monitoring, particle size, number concentration, and concentration stability were precisely controlled, and the measured deposition deviation (less than 7%) closely mirrored the lung deposition variability observed in actual animals (rats). These results demonstrate that this in vitro methodology can meet regulatory inhalation guidelines, providing a robust framework for transitioning from animal testing to cell-based testing

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This study compared and analyzed the atmospheric particle charging characteristics in polar regions (the Antarctic King Sejong Station and the Arctic Dasan Station), where anthropogenic factors are minimal, and a mid-latitude urban area (Ansan, South Korea) using a self-developed aerosol electrical mobility spectrum analyzer (AEMSA). The analysis revealed that while the urban area of Ansan maintained a well-balanced state with a positive-to-negative charged particle ratio close to 1:1, the Antarctic and Arctic regions exhibited a clear imbalance, with positively charged particle concentrations being 1.4 and 2.8 times higher than negatively charged ones, respectively. 

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